BOLLING RESEARCH GROUP
Food chemistry and health
Aronia berry plant

King ES et al. Time of harvest affects United States-grown Aronia mitschurinii berry polyphenols, °Brix, and acidity.

See the article.
Apples on tree

The Bolling Research Group has developed new methods to isolate polyphenols from fruit juice to use as food ingredients, dietary supplements, or drugs.

See the patent.
Cranberry picture

Latest publication on analysis of cranberry juice.
Photo credit: Sevie Kenyon/UW-Madison College of Agriculture and Life Sciences

See the paper.

Publications

Bibliography

PATENTS

RECENT PUBLICATIONS

  • Hasegawa Y, Noll AL, Lang DJ, Akfaly E, Liu Z, Bolling BW. Low-fat yogurt consumption maintains biomarkers of immune function relative to nondairy control food in women with elevated BMI: a randomized controlled crossover trial. Nutrition Research. 2024;129:1-13.
  • Liu C, Girard AL, Hartel RW, Bolling BW. Improved analysis of grape seed extract by liquid chromatography-high resolution mass spectrometry (LC-HRMS) reveals that proanthocyanidin-protein interaction mechanisms in cream depend on degree of polymerization. Food Chemistry. 2024;451:139432.
  • Liu C, Bolling BW. Dietary proanthocyanidins for improving gut immune health. Current Opinion in Food Science. 2024;56:101133.
  • Njami RM, Elombo FK, Pechangou SN, Bolling B, Njayou FN, Moundipa PF. Journal of Pharmacognosy and Phytochemistry. 2024;13(3):06-12.
  • Hasegawa Y, Bolling BW. Technological approaches to improve food quality for human health. In:  Temple NJ, Wilson T, Jacobs Jr DR, Bray GA (eds) Nutritional Health. 2023. pp 345-56.
  • Bolling BW. Anthocyanins and health: Are fruit and vegetable dietary recommendation outdated in the context of ultraprocessed foods? Nutrition Research. 2023;115:61-62.
  • Dorris MR, Zeller WE, Bolling BW. 1H−13C HSQC−NMR Analysis of Cranberry (Vaccinium Macrocarpon) Juice Defines the Chemical Composition of Juice Precipitate. Journal of Agricultural and Food Chemistry. 2023;71:10710-10717.
  • Wicks CJ, Bolling BW, Hartel RW. Effects of tannic acid on proteins and fat in cream. Food Production, Processing and Nutrition.  2023;5:51.
  • Hasegawa Y, Khongkomolsakul W, Bolling BW. Extracts of plant-based yogurts inhibit recombinant human angiotensin converting enzyme 2 (rhACE2) activity. Journal of Food Bioactives. 2023;21:21-27.
  • Hasegawa Y, Bolling BW. Yogurt consumption for improving immune health. Current Opinion in Food Science. 2023;51:101017
  • Bolling BW, Aune D, Noh H, Petersen KS, Freisling H. Dried fruits, nuts, and cancer risk and survival: A review of the evidence and future research directions. Nutrients. 2023;15(6):1443. [In Proceeding from the NUTS 2022 International Conference Special Issue]
  • Hasegawa Y, Pei R, Raghuvanshi, Liu Z, Bolling BW. Yogurt supplementation attenuates insulin resistance in obese mice by reducing metabolic endotoxemia and inflammation. Journal of Nutrition. 2023;153(3):703-12.
  • Ceylan FD, Adrar N, Bolling BW, Capanoglu E. Investigation on the current valorisation of hazelnut by-products and their potential. Biotechnology and Genetic Engineering Reviews. 2022;Dec 28:1-36.
  • Ale EC, Ibanez RA, Wilbanks DJ, Peralta GH, Ceylan FD, Binetti AG, Bolling BW, Lucey JA. Technological role and metabolic profile of two probiotic EPS-producing strains with potential application in yoghurt: Impact on rheology and release of bioactive peptides. International Dairy Journal. 2023;137:105533.
  • Mahoney JD, Wang S, Iorio LA, Wegrzyn JL, Dorris M, Martin D, Bolling BW, Brand MH, Wang H. De novo assembly of fruit transcriptome identifies AmMYB10 as a key regulator of anthocyanin biosynthesis in Aronia melanocarpa. BMC Plant Biology. 2022; 22:143.
  • King ES, Noll A, Glenn S, Bolling BW. Refrigerated and frozen storage impact aronia berry quality.  Food Production, Processing and Nutrition. 2022; 4:3.
  • King ES, Cho J, Li H, Jiang X, Madler AK, Weishair MK, Glenn S, Brand MH, Xu C, Bolling BW. Time of harvest affects United States-grown Aronia mitschurinii berry polyphenols, °Brix, and acidity.  Journal of Agriculture and Food Research. 2021; 6:100248.
  • Dorris, MR, Bolling BW. Cranberry (Vaccinium macrocarpon) juice precipitate pigmentation is mainly polymeric colors and has limited impact on soluble anthocyanin loss. Antioxidants. 2021; 10(11):1788.
  • Hess JM, Stephensen CB, Kratz M, Bolling BW. Exploring the links between diet and inflammation: Dairy foods as a case study. Advances in Nutrition. 2021; 12(S1):1S-13S.
  • Liu X, Martin DA, Valdez JC, Sudakaran S, Rey F, Bolling BW. Aronia berry polyphenols have matrix-dependent effects on the gut microbiota. Food Chemistry. 2021; 359: 129831.
  • Alasalvar C, Chang SK, Bolling BW, Oh WY, Shahidi F. Specialty seeds: Nutrients, bioactives, bioavailability, and health benefits: A comprehensive Review. Critical Reviews in Food Science and Food Safety. 2021; 1-46.
  • Liu X, Raghuvanshi R, Cylan FD, Bolling BW. Quercetin and its metabolites inhibit recombinant human angiotensin converting enzyme 2 (ACE2) activity. Journal of Agricultural and Food Chemistry. 2020; 68:13982-13989.
  • King ES, Bolling BW. Composition, polyphenol bioavailability, and health benefits of aronia berry: a review. Journal of Food Bioactives. 2020; 11: 13-30.
  • Valdez JC, Cho J, Bolling BW. Aronia berry inhibits disruption of Caco-2 intestinal barrier function. Archives of Biochemistry and Biophysics. 2020; 688: 108409.
  • Pei R, Liu X, Bolling BW. Flavonoids for gut health. Current Opinion in Biotechnology. 2020; 61: 153-159.
  • Carmona-Hernandez JC, Taborda-Ocampo G, Valdez JC, Bolling BW, Gonzalez-Correa CH. Polyphenol extracts from three Columbian passifloras (passion fruit) prevent inflammation-induced barrier dysfunction of Caco-2 cells. Molecules. 2019; 24: E4614 (1-17).
  • Hirahatake KM, Bruno RS, Bolling BW, Blesso C, Alexander LM, Adams SH. Dairy foods and dairy fats: New perspectives on pathways implicated in cardiometabolic health. Advances in Nutrition, 2020; 11(2), 266-79.
  • Pei R, Liu J, Martin DA, Valdez JC, Jeffery J, Barrett-Wilt GA, Liu Z, Bolling BW. Aronia berry supplementation inhibits T cell transfer-induced colitis by decreasing oxidative stress. Nutrients. 2019;11(6), 1316.
  • Rodriguez-Castano, GP, Dorris MR, Liu X, Bolling BW, Acosta-Gonzalez A, Rey FE. Bacteroides thetaiotaomicron starch utilization promotes quercetin degradation and butyrate production by Eubacterium ramulus. Frontiers in Microbiology. 2019; 10 (1145).
  • Valdez JC, Bolling BW. Anthocyanins and intestinal barrier function: a review. Journal of Food Bioactives. 2019;5:18-30.
  • Pei R, Martin DA, Liu J, Kerby R, Rey F, Smyth JA, Liu Z, Bolling BW. Dietary prevention of colitis by aronia berry is mediated through increased Th17 and Treg. Molecular Nutrition & Food Research. 2019:1800985:1-11.
  • Yang H, Wang W, Romano KA, Gu M, Sanidad KZ, Kim D, Yang J, Schmidt B, Panigrahy D, Pei R, Martin DA, Ozay EI, Wang Y, Song M, Bolling BW, Xiao H, Minter LM, Yang G-Y, Liu Z, Rey FE, Zhang G. Common antimicrobial additives increase colonic inflammation and colitis-associated colon tumorigenesis in mice. Science Translational Medicine. 2018;10:eaan4116.
  • Pei R, DiMarco DM, Putt KK, Martin DA, Chitchumroonchokchai C, Bruno RS, Bolling BW. Pre-meal low-fat yogurt consumption reduces postprandial inflammation and markers of endotoxin exposure in healthy premenopausal women in a randomized controlled trial. Journal of Nutrition. 2018;148:1-7.
  • Dorris MR, Voss DM, Bollom M, Krawiec-Thayer M, Bolling BW. Browning index of anthocyanin-rich fruit juice depends on pH and anthocyanin loss more than the gain of soluble polymeric pigments. Journal of Food Science. 2018;83:911-921.
  • Martin D, Smyth JA, Liu Z, Bolling BW. Aronia berry (Aronia mitschurinii ‘Viking’) inhibits colitis in mice and inhibits T cell tumour necrosis factor-α secretion. Journal of Functional Foods. 2018;44:48-57.
  • Pei R, DiMarco DM, Putt KK, Martin DA, Gu Q, Chitchumroonchokchai C, White HM, Scarlett CO, Bruno RS, Bolling BW. Low-fat yogurt consumption reduces chronic inflammation and inhibits markers of endotoxin exposure in healthy women: a randomized controlled trial. British Journal of Nutrition. 2017;118:1043-1051.
  • Bolling, B. Almond polyphenols: methods of analysis, contribution to food quality and health promotion. Comprehensive Reviews in Food Science and Food Safety. 2017;16:346-68.
  • Putt K, Pei R, White HM, Bolling BW. Yogurt inhibits intestinal barrier dysfunction in Caco-2 cells by increasing tight junctions. Food & Function. 2017;8:406-414.
  • Xie L, Vance T, Kim B, Lee SG, Caceres C, Wang Y, Lee J-Y, Chun OC, Bolling B. Aronia berry polyphenol consumption reduces plasma total and LDL cholesterol in former smokers without lowering biomarkers of inflammation and oxidative stress: a randomized controlled trial. Nutrition Research. 2017;37:67-77